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Emergence of methicillin resistance predates the clinical use of antibiotics

Nature - issue - St, 01/05/2022 - 00:00

Nature, Published online: 05 January 2022; doi:10.1038/s41586-021-04265-w

Methicillin-resistant strains of Staphylococcus aureus appeared in European hedgehogs in the pre-antibiotic era as a co-evolutionary adaptation to antibiotic-producing dermatophytes and have spread within the local hedgehog populations and between hedgehogs and secondary hosts.

RNA profiles reveal signatures of future health and disease in pregnancy

Nature - issue - St, 01/05/2022 - 00:00

Nature, Published online: 05 January 2022; doi:10.1038/s41586-021-04249-w

Expression signatures from cell-free RNA of pregnant women can be used to reveal normal biology of pregnancy and predict development of pre-eclampsia.

Depressed 660-km discontinuity caused by akimotoite–bridgmanite transition

Nature - issue - St, 01/05/2022 - 00:00

Nature, Published online: 05 January 2022; doi:10.1038/s41586-021-04157-z

X-ray diffraction experiments indicate that the depression of the Earth’s 660-kilometre seismic discontinuity beneath cold subduction zones is caused by a phase transition from akimotoite to bridgmanite, leading to slab stagnation.

Behavioural immune landscapes of inflammation

Nature - issue - St, 01/05/2022 - 00:00

Nature, Published online: 05 January 2022; doi:10.1038/s41586-021-04263-y

High-dimensional datasets derived from time-resolved live imaging of leukocytes in mice were used to identify leukocyte identities and dynamic neutrophil states with high cellular resolution.

A speech planning network for interactive language use

Nature - issue - St, 01/05/2022 - 00:00

Nature, Published online: 05 January 2022; doi:10.1038/s41586-021-04270-z

Using intracranial electrocorticography and a series of motor tasks, a speech planning network that is central to natural language generation during social interaction is identified.

A stellar stream remnant of a globular cluster below the metallicity floor

Nature - issue - St, 01/05/2022 - 00:00

Nature, Published online: 05 January 2022; doi:10.1038/s41586-021-04162-2

Observations of a stellar stream below the metallicity floor for a disrupted globular cluster are described.

Iron pnictides and chalcogenides: a new paradigm for superconductivity

Nature - issue - St, 01/05/2022 - 00:00

Nature, Published online: 05 January 2022; doi:10.1038/s41586-021-04073-2

The progress and the outstanding issues in understanding the correlated phases in the unconventional iron-based superconductors is reviewed.

A naturally inspired antibiotic to target multidrug-resistant pathogens

Nature - issue - St, 01/05/2022 - 00:00

Nature, Published online: 05 January 2022; doi:10.1038/s41586-021-04264-x

The discovery and synthesis of a colistin congener provide a promising clinical lead against mcr-1-encoding colistin-resistant pathogens, which are responsible for an increasing number of deaths from antibiotic-resistant infections.

A 16-parts-per-trillion measurement of the antiproton-to-proton charge–mass ratio

Nature - issue - St, 01/05/2022 - 00:00

Nature, Published online: 05 January 2022; doi:10.1038/s41586-021-04203-w

Multiple high-precision measurement campaigns at CERN of the antiproton-to-proton charge-to-mass ratio—to a precision of 16 parts per trillion—in a cryogenic multi-Penning trap offer no evidence of charge–parity–time violation, and set stringent limits on the clock-weak-equivalence principle.

Crystallization of bosonic quantum Hall states in a rotating quantum gas

Nature - issue - St, 01/05/2022 - 00:00

Nature, Published online: 05 January 2022; doi:10.1038/s41586-021-04170-2

Spontaneous crystallization of atoms occurs in a rotating ultracold Bose–Einstein condensate occupying the lowest Landau level, behaviour that is related to a quantum hydrodynamic instability driven by shear forces.

Mirror symmetry validated for proton and its antimatter twin

Nature - issue - St, 01/05/2022 - 00:00

Nature, Published online: 05 January 2022; doi:10.1038/d41586-021-03798-4

A comparison of the charge-to-mass ratio for the proton and the antiproton has been performed with record-breaking precision — the best such test yet for a mirror-like symmetry that relates matter and antimatter.

The magnetic field of a molecular cloud revealed

Nature - issue - St, 01/05/2022 - 00:00

Nature, Published online: 05 January 2022; doi:10.1038/d41586-021-03803-w

A combination of standard and new observational techniques has been used to detect the magnetic field of a molecular cloud — a region of the interstellar medium that collapses during star formation. The results suggest that such clouds are primed for collapse earlier than was typically assumed.

A blood test to predict complications of pregnancy

Nature - issue - St, 01/05/2022 - 00:00

Nature, Published online: 05 January 2022; doi:10.1038/d41586-021-03801-y

Cell-free RNA transcripts in maternal blood can be analysed to monitor the progression of pregnancy and to predict a potentially harmful pregnancy-specific condition called pre‑eclampsia.

Ring in the new

Nature - issue - St, 01/05/2022 - 00:00

Nature, Published online: 05 January 2022; doi:10.1038/d41586-021-03745-3

Upholding traditions.

How researchers can help fight climate change in 2022 and beyond

Nature - issue - St, 01/05/2022 - 00:00

Nature, Published online: 05 January 2022; doi:10.1038/d41586-021-03817-4

COP26 energized the global effort to halt global warming. Research is now crucial to monitoring progress and creating solutions.

Daily briefing: Chemist Charles Lieber convicted of hiding his ties to China

Nature - issue - Út, 01/04/2022 - 00:00

Nature, Published online: 04 January 2022; doi:10.1038/d41586-022-00014-9

Renowned scientist convicted as part of the US crackdown on researchers with connections to China. Plus, safety fears following fatal explosions in laboratories, and farewell to three scientific giants: Richard Leakey, E. O. Wilson and Thomas Lovejoy.

Elizabeth Holmes verdict: researchers share lessons learned for science

Nature - issue - Út, 01/04/2022 - 00:00

Nature, Published online: 04 January 2022; doi:10.1038/d41586-022-00006-9

Theranos case highlights the importance of peer review for biotech entrepreneurs, scientists say.

Rivers buffer a vast sea against climate-change impacts

Nature - issue - Út, 01/04/2022 - 00:00

Nature, Published online: 04 January 2022; doi:10.1038/d41586-021-03843-2

As global temperatures rise, parts of the Gulf of Mexico are undergoing less acidification than expected — for now.

A cloud named Maggie: space streamer could birth new stars

Nature - issue - Út, 01/04/2022 - 00:00

Nature, Published online: 04 January 2022; doi:10.1038/d41586-021-03848-x

Giant hydrogen filament is one of the longest features of its type in the Galaxy.

Tomb reveals warrior women who roamed the ancient Caucasus

Nature - issue - Út, 01/04/2022 - 00:00

Nature, Published online: 04 January 2022; doi:10.1038/d41586-021-03828-1

Dagger and arrows interred in a grave 3,000 years ago provide evidence of female warriors.

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