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How a child’s heart health could be decided before birth

Nature - issue - St, 06/09/2021 - 00:00

Nature, Published online: 09 June 2021; doi:10.1038/d41586-021-01451-8

Lifestyle is a major contributor to heart disease in adults, but risk factors such as genetics and parent lifestyle can also have an effect.

Embrace the WHO’s new naming system for coronavirus variants

Nature - issue - St, 06/09/2021 - 00:00

Nature, Published online: 09 June 2021; doi:10.1038/d41586-021-01508-8

The World Health Organization’s system should have come earlier. Now, media and policymakers need to get behind it.

A base-pair view of interactions between genes and their enhancers

Nature - issue - St, 06/09/2021 - 00:00

Nature, Published online: 09 June 2021; doi:10.1038/d41586-021-01494-x

A technique reveals how folded chromosomal DNA interacts in the nucleus, providing information at the level of single base pairs. The achievement offers an unprecedented level of detail about how gene activity is regulated.

AI system outperforms humans in designing floorplans for microchips

Nature - issue - St, 06/09/2021 - 00:00

Nature, Published online: 09 June 2021; doi:10.1038/d41586-021-01515-9

A machine-learning system has been trained to place memory blocks in microchip designs. The system beats human experts at the task, and offers the promise of better, more-rapidly produced chip designs than are currently possible.

Immune cells that remember inflammation could offer treatment targets for atherosclerosis

Nature - issue - St, 06/09/2021 - 00:00

Nature, Published online: 09 June 2021; doi:10.1038/d41586-021-01454-5

A type of immune-cell priming called trained immunity is helping researchers to understand the disease mechanisms behind the build up of fatty deposits in arteries.

Cells or drugs? The race to regenerate the heart

Nature - issue - St, 06/09/2021 - 00:00

Nature, Published online: 09 June 2021; doi:10.1038/d41586-021-01457-2

Researchers are debating how to convince the heart to heal itself instead of laying down scar tissue after a heart attack.

Ranking the risk of heart disease

Nature - issue - St, 06/09/2021 - 00:00

Nature, Published online: 09 June 2021; doi:10.1038/d41586-021-01452-7

By accounting for the additive effect of multiple genetic variants, researchers can develop a system that improves their ability to identify the most vulnerable.

Is there more to a healthy-heart diet than cholesterol?

Nature - issue - St, 06/09/2021 - 00:00

Nature, Published online: 09 June 2021; doi:10.1038/d41586-021-01455-4

A high-fat diet is thought to increase the risk of a heart attack. But some say that the long-held dogma of ‘bad’ cholesterol might be flawed.

Squeezed light improves sensitivity of microscopy technique

Nature - issue - St, 06/09/2021 - 00:00

Nature, Published online: 09 June 2021; doi:10.1038/d41586-021-01514-w

Vibrational signals from molecules can provide contrast in bioimaging techniques, but are difficult to detect. Light in a ‘squeezed’ quantum state has been used to reveal molecular vibrational signals previously obscured by noise.

Women’s heart health is not just about hormones

Nature - issue - St, 06/09/2021 - 00:00

Nature, Published online: 09 June 2021; doi:10.1038/d41586-021-01458-1

Heart-disease risk increases as women get older but explanations that centre on changes after menopause don’t tell the full story.

Google’s AI approach to microchips is welcome — but needs care

Nature - issue - St, 06/09/2021 - 00:00

Nature, Published online: 09 June 2021; doi:10.1038/d41586-021-01507-9

Artificial intelligence can help the electronics industry to speed up chip design. But the gains must be shared equitably.

Inflammation in heart disease: do researchers know enough?

Nature - issue - St, 06/09/2021 - 00:00

Nature, Published online: 09 June 2021; doi:10.1038/d41586-021-01453-6

Anti-inflammatory therapies for cardiovascular disease are nearing the clinic. But whether scientists understand how inflammation contributes to fatty-deposit build-up well enough to target it effectively is open to debate.

COVID’s cardiac connection

Nature - issue - St, 06/09/2021 - 00:00

Nature, Published online: 09 June 2021; doi:10.1038/d41586-021-01456-3

Coronavirus infections might cause lasting harm to the heart, even in those who have never had symptoms.

Quantum keys dial up tamper-proof conference calls

Nature - issue - St, 06/09/2021 - 00:00

Nature, Published online: 09 June 2021; doi:10.1038/d41586-021-01534-6

A new experiment efficiently distributes the highly secure keys to four parties instead of the typical two.

A coronavirus variant’s strategy for world dominance

Nature - issue - St, 06/09/2021 - 00:00

Nature, Published online: 09 June 2021; doi:10.1038/d41586-021-01540-8

The rapid spread of the B.1.1.7 variant — also called Alpha — might be linked to its ability to dampen the body’s initial immune response.

The woman who spoke for the sea

Nature - issue - St, 06/09/2021 - 00:00

Nature, Published online: 09 June 2021; doi:10.1038/d41586-021-01555-1

An element of regret.

Business of science: The setbacks that can help your start-up succeed

Nature - issue - St, 06/09/2021 - 00:00

Nature, Published online: 09 June 2021; doi:10.1038/d41586-021-01007-w

Cash-flow challenges and team tensions are just two of the issues a fledgling business can face. Learn from them and move on, say seasoned entrepreneurs.

The four most urgent questions about long COVID

Nature - issue - St, 06/09/2021 - 00:00

Nature, Published online: 09 June 2021; doi:10.1038/d41586-021-01511-z

Scientists are starting to get insights into the lingering disorder that affects some people infected with SARS-CoV-2 — but many mysteries remain unsolved.

Immunogenicity of Ad26.COV2.S vaccine against SARS-CoV-2 variants in humans

Nature - issue - St, 06/09/2021 - 00:00

Nature, Published online: 09 June 2021; doi:10.1038/s41586-021-03681-2

Immunogenicity of Ad26.COV2.S vaccine against SARS-CoV-2 variants in humans

Managing the ‘dataome’, medical misogyny, and the problem with palm oil: Books in brief

Nature - issue - St, 06/09/2021 - 00:00

Nature, Published online: 09 June 2021; doi:10.1038/d41586-021-01513-x

Andrew Robinson and Sara Abdulla review five of the week’s best science picks.

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