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Low protease activity in B cell follicles promotes retention of intact antigens after immunization | Science

Science - issue - Pá, 01/27/2023 - 15:01
Spatially heterogeneous protease activity within lymph nodes modulates humoral responses to vaccination.

Earthlike planets should readily form around other stars, meteorites suggest

Science - issue - Čt, 01/26/2023 - 20:00
Samples from space rocks suggest water and light elements are present in warm inner part of planet-forming disks

Encoding of environmental illumination by primate melanopsin neurons | Science

Science - issue - Čt, 01/26/2023 - 15:01
A rare type of primate retinal neuron encodes irradiance by blurring across space, time, and wavelength.

Meteorites have inherited nucleosynthetic anomalies of potassium-40 produced in supernovae | Science

Science - issue - Čt, 01/26/2023 - 15:01
Potassium isotope ratios in meteorites show nucleosynthetic anomalies that constrain the assembly of Earth.

Nucleosynthetic isotope anomalies of zinc in meteorites constrain the origin of Earth’s volatiles | Science

Science - issue - Čt, 01/26/2023 - 15:01
Zinc isotope ratios in meteorites show nucleosynthetic anomalies that constrain the assembly of Earth.

Complex scaffold remodeling in plant triterpene biosynthesis | Science

Science - issue - Čt, 01/26/2023 - 15:01
Genetic and biochemical work uncover the biosynthetic pathway of biologically active triterpenes.

Truchet-tile structure of a topologically aperiodic metal–organic framework | Science

Science - issue - Čt, 01/26/2023 - 15:01
A metal-organic framework with ordered nodes but disordered linkers contains aperiodic micropores.

Structural basis of mammalian respiratory complex I inhibition by medicinal biguanides | Science

Science - issue - Čt, 01/26/2023 - 15:01
Biguanides inhibit complex I by binding in the quinone channel and exert a localized chaotropic effect.

In Other Journals | Science

Science - issue - Čt, 01/26/2023 - 15:01
Editors’ selections from the current scientific literature

In Science Journals | Science

Science - issue - Čt, 01/26/2023 - 15:01
Highlights from the Science family of journals

NextGen Voices call for submissions: The future of scientific societies | Science

Science - issue - Čt, 01/26/2023 - 15:01
Add your voice to Science! Our new NextGen Voices survey for young scientists is open: AAAS (the publisher of Science) turns 175 years old this year! AAAS’s mission is to advance science, engineering, and innovation throughout the world for the benefit of all. Have scientific societies played a role in your career? Are scientific societies prepared to support scientists in a changing world? What is the most important role they could play, and what changes must they make to be more effective?

Animal agriculture’s potential financial risks | Science

Science - issue - Čt, 01/26/2023 - 15:01
With a contribution of 16.5% to global greenhouse gas emissions (1), animal agriculture is a key driver of climate change, second only to fossil fuels. Soy production—three-quarters of which is used as livestock feed (2)—and beef production are the top two drivers of deforestation in the Amazon (3). Livestock farming poses a risk to more than 17,900 species listed on the International Union for Conservation of Nature’s Red List of Threatened Species (4). Because the environmental threats posed by animal agriculture can translate into a range of business risks for animal protein suppliers, environmentally responsible businesses are safer investments than those that cause harm (5). Therefore, businesses within the animal agriculture industry should measure and disclose their environmental impacts, and financial institutions should protect themselves from losses by investing in businesses that are good environmental stewards.

Hidden costs of Europe’s deforestation policy | Science

Science - issue - Čt, 01/26/2023 - 15:01
The European Union (EU) soon plans to implement a law that would limit the importation of products known to drive deforestation (1), including Brazilian products originating from deforested areas in the Amazon. The law’s goal of removing incentives that lead to forest degradation is laudable, given the rate of deforestation (2). However, by focusing on forests alone, the law is potentially putting other ecosystems at greater risk, as well as overlooking the reliance of forests on adjacent regions. To prevent unintended consequences, the EU should expand the law to include ecosystems other than forests.

EU deforestation law overlooks emerging crops | Science

Science - issue - Čt, 01/26/2023 - 15:01
HomeScienceVol. 379, No. 6630EU deforestation law overlooks emerging cropsBack To Vol. 379, No. 6630 Full accessLetter Share on EU deforestation law overlooks emerging cropsLuke L. Powell [email protected], Joana Capela, [...] , Patrícia Guedes, and Pedro Beja+1 authors fewerAuthors Info & AffiliationsScience26 Jan 2023Vol 379, Issue 6630pp. 340-341 PREVIOUS ARTICLEA population pessimist turns 90…

A population pessimist turns 90 | Science

Science - issue - Čt, 01/26/2023 - 15:01
Paul Ehrlich reflects on life, love, and the science and politics of the human predicament

Science in the age of podcasts | Science

Science - issue - Čt, 01/26/2023 - 15:01
A powerful 21st-century medium affords new opportunities for learning and creative thinking

Dieter Oesterhelt (1940–2022) | Science

Science - issue - Čt, 01/26/2023 - 15:01
Pioneer of membrane protein research

Neurons share an intense load | Science

Science - issue - Čt, 01/26/2023 - 15:01
Time-of-day–detecting cells in the eye give customized responses to light intensity

Infection infidelities drive innate immunity | Science

Science - issue - Čt, 01/26/2023 - 15:01
Unsuccessful pathogenic activities may be key to activating host defenses to infection

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